Comparison between different fluids given before spinal anaesthesia for the prevention of spinal anaesthesia induced decrease in blood pressure in patients undergoing elective lower segment caesarean section

Combined colloid preload and crystalloid co-load versus crystalloid co-load alone for the prevention of subarachnoid block induced hypotension in patients undergoing elective lower segment caesarean section:A randomized comparative study - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067689

Enrollment

104

Registered

2024-05-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: Effect of fluids (colloid preload and crystalloid co-load)in spinal anaesthesia in patients undergoing elective LSCS: In group A1 500ml colloid preload and 500mlcrystalloid co-load in s

Eligibility

Inclusion criteria

Inclusion criteria: 1.American Society of Anaesthesiology (ASA) physical status II parturients scheduled for elective caesarean delivery under subarachnoid block. 2.Pregnant females with full term pregnancy of reproductive age 20-35 years without any coexisting disease

Exclusion criteria

Exclusion criteria: A known sensitivity to any study drug, Patient with coexisting disease like Chronic or Pregnancy induced Hypertension, diabetes mellitus, history of Cardiac or Respiratory disease or with impaired kidney or liver function and severe anemia Patient having any contraindication to spinal anaesthesia Onset of labour or multiple pregnancy or polyhydroamnios or known fetal abnormalities Patient with body mass index more than 40kg per square metre

Design outcomes

Primary

Measure	Time frame
Incidence of hypotension , systolic blood pressure less than 80% of the baselineTimepoint: Every minute From the time of subarachnoid block for first five minutes and then every three minutes till clamping of umbilical cord	—

Secondary

Measure	Time frame
•Vasopressor requirement •APGAR score of neonate at 1 and 5 minutes •Incidence of nausea and vomiting Timepoint: From the time of subarachnoid block till 5 minutes of child birth	—

Countries

India

Contacts

Public ContactDr Lalita Chaudhary

ABVIMS and Dr. RML hospital

lalitachaudhary055@gmail.com9968299710

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026