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In this study, the researchers want to understand how effective a drug called dexmedetomidine is in keeping the patients vital signs, such as blood pressure and heart rate, within a normal range during a medical procedure called modified electroconvulsive therapy (m-ECT).

To evaluate the efficacy of parenteral Dexmedetomidine in attenuating hemodynamic responses and post- ictal agitation in patients undergoing modified electroconvulsive therapy - Nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067681
Enrollment
100
Registered
2024-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Drug DEXMEDITOMEDINE: On arrival in the ECT room, all patients will have standard monitoring like pulse oximetry (SpO2), electrocardiography (ECG) and non- invasive blood pressure (NI

Sponsors

Pt B D Sharma post graduate institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: belonging to American Society of Anaesthesiologists (ASA) physical status of I-II, who are diagnosed with mood disorder and undergoing modified ECT

Exclusion criteria

Exclusion criteria: Following patients will be excluded from study 1)Refusal to consent by relatives 2) History of underlying renal, hepatic, cardiac and pulmonary diseases 3)History of head trauma 4) Patients who do not have seizures after receiving m – ECT.

Design outcomes

Secondary

MeasureTime frame
1) Motor seizure duration (in seconds) 2) Time to spontaneous breathing (in seconds) 3) Responding time to verbal commands (in minutes)Timepoint: 1)SBP,SBP,MAP,HR,RPP at 1 min, 3 min,5 min,10 min and 20 min. 2)Motor seizure duration 3) Emergence agitation score at 30min

Primary

MeasureTime frame
Effect on hemodynamic responses and post ictal agitationTimepoint: 15 min before ECT and upto 20 min after ECT

Countries

India

Contacts

Public ContactDr Kumili Raj Bhagavan

Pt B D Sharma post graduate institute of medical sciences

k.rajbhagavan@gmail.com8520937477

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026