Assess the effect of Liquorice gel as local drug delivery agent for treatment of Chronic Periodontitis

Assessment of the efficacy of subgingivally delivered Liquorice gel on clinical parameters and Prostaglandin E2 level in Chronic Periodontitis : A Clinico-Biochemical study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067674

Enrollment

Registered

2024-05-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Liquorice gel: Agent- Lab prepared 0.1% concentrated liquorice gel in polymeric base with added preservatives. Agent-Lab prepared polymeric base gel with preservatives. Dose-Depends upo

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with moderate chronic periodontitis with bilateral nearly symmetrical sites having pocket depth of =4mm but =6mm. 2. Systemically healthy patients.

Exclusion criteria

Exclusion criteria: 1. Medically compromised patients. 2. Smokers. 3. Pregnant or lactating women. 4. Patients who had undergone periodontal therapy or used antibiotics/ analgesics/ anti-inflammatory drugs in the last 6 months.

Design outcomes

Primary

Measure	Time frame
Changes in Plaque index (PI), Gingival index (GI), Probing Pocket Depth (PPD), Clinical Attachment Level (CAL) and PGE2 levels in GCFTimepoint: Baseline (Before SRP & gel placement) After 15 days of gel placement After 30 days of gel placement	—

Secondary

Measure	Time frame
Changes in Plaque index (PI) and Gingival index (GI)Timepoint: Baseline (Before SRP & gel placement) After 15 days of gel placement After 30 days of gel placement	—

Countries

India

Contacts

Public ContactDr. Diksha Gupta

UTTAR PRADESH UNIVERSITY OF MEDICAL SCIENCES

drbipinkumaryadavperio@gmail.com8449619482

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026