FindTrial
Sign In

Comparison of High flow nasal cannula and Non invasive ventilation in type 1 respiratory failure

Highflow nasal cannula versus noninvasive ventilation in the prevention of escalation to invasive mechanical ventilation in patients with acute hypoxemic respiratory failure. A Randomised Comparative Interventional Study at SMS Medical College - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067659
Enrollment
80
Registered
2024-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: prevention of escalation to invasive mechanical ventilation in patients with acute hypoxemic respiratory failure: prevention of escalation to invasive mechanical ventilation in patients

Sponsors

Department of Anaesthesiology SMS Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient willing to give consent Patients having AHRF defined by PaO2/FiO2 less than or equal to 300mmhg Patient not responding to conventional oxygen therapy Patient requiring ventilator support due to increased respiratory rate

Exclusion criteria

Exclusion criteria: Absolute indication for intubation Contraindication to NIV PaCO2 more than 45mmhg Chronic respiratory failure

Design outcomes

Primary

MeasureTime frame
To Assess Need for Invasive Mechanical Ventilation In Patients of Acute Hypoxemic Respiratory Failure.Timepoint: until Invasive Mechanical Ventilation—

Secondary

MeasureTime frame
1.To measure vital parameters (SBP, DBP, MAP, HR, RR, SPO2) 2.To assess respiratory acidosis by recording ABG. 3.To assess duration of lCU stay. 4.To measure hospital mortality. Timepoint: 1.At admission, 12hours, 24hours,36hours, 72hours 2.AT 1hour ,6hours ,24hours ,48hours.—

Countries

India

Contacts

Public ContactDr Kavita M

Sms medical college

drniharsharma@gmail.com9314044376

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026