Relation between Nitrous oxide exposure during Anaesthesia and vitamin B12 deficiency in medical professionals

correlation between nitrous oxide exposure and vitamin b12 deficiency in health care personnel - nil

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

CTRI

Registry ID

CTRI/2024/05/067600

Enrollment

194

Registered

2024-05-17

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nitrous Oxide: Nitrous Oxide and oxygen is used in 50 : 50 %, through inhalational route

Eligibility

Inclusion criteria

Inclusion criteria: 1.Health care personnel who are exposed for more than 3 years working more than 5hours or more per day exposed to nitrous oxide. and control group consists of health care personnel not exposed to nitrous oxide. 2.Health care personnel exposed to nitrous oxide and health care personnel not exposed to nitrous oxide who agrees and gives consent to the above study.

Exclusion criteria

Exclusion criteria: who have history 1.Anemia (hemoglobin 2.Alchoholics 3.smokers 4.personnel with neurological deficits (tremors, myopathy, dementia, depression, stroke, psychosis, parasthesias, numbness, autonomic neuropathy) 5.personnel with malabsorption syndromes, glossitis, mucocutaneous ulcer. 6.uncontrolled type two diabetes 7. Peptic ulcer disease, hyperacidity, gastritis, chrons disease. 8. participants on metformin, proton pump inhibitors, H2 histamine receptor Antagonists.

Design outcomes

Primary

Measure	Time frame
To Corelate between number of years of exposure to Nitrous oxide and Vitamin B12 deficiencyTimepoint: The blood sample will be taken and sent for laboratory for complete blood count, peripheral smear and vitaminB12 estimation	—

Secondary

Measure	Time frame
To find out the correlation between number of years of exposure to nitrous oxide and vitamin b12 deficiencyTimepoint: To find out the correlation between number of years of exposure to nitrous oxide and vitamin b12 deficiency	—

Countries

India

Contacts

Public ContactDr Puneeth Kumar S

ESIC Medical college and PGIMSR Rajajinagar bangalore karnataka

punianaesth@gmail.com9036165026

Outcome results