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comparison of recovery after surgery and intraoperative requirement of inhalational agent in opioid based anaesthesia versus opioid free anaesthesia in patients undergoing laparoscopic surgeries

comparison of effect of opioid free anaesthesia versus opioid based anaesthesia on post operative recovery profile and consumption of sevoflurane in patients undergoing laparoscopic surgeries: a randomised controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067583
Enrollment
80
Registered
2024-05-17
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: opioid free anaesthesia: Patients will receive opioid free anaesthesia using intravenous combined ketamine and propofol infusion (total volume of 20cc containing 5mg/cc of ketamine and

Sponsors

Bangalore medical college and research institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are willing to give informed consent. Patients of age 18 to 60 years. ASA grades 1 and 2. Patients with BMI 19 to 25 Patients undergoing laparoscopic surgeries Duration of surgery 90 minutes

Exclusion criteria

Exclusion criteria: Patient refusal. Patients with history of allergy to egg, soya, opioids. Patients with severe systemic diseases. Patient requiring postoperative mechanical ventilation. Patients with neurologic or psychiatric illness. Patients with past history of cardiovascular diseases.

Design outcomes

Primary

MeasureTime frame
Dosage of sevoflurane consumed intraoperatively. Timepoint: PSI values and end tidal sevoflurane concentration will be monitored every 5 minutes for the first 30 minutes followed by every 10 minutes for the next one hour.

Secondary

MeasureTime frame
various scoring systems like vas score, apfel score, modified aldrete score for recovery profile.Timepoint: various scoring systems like vas score, apfel score, modified aldrete score will be monitored in immediate post operative period and then at 30 minutes, 1 hour, 2 hours, 4 hours, 8 hours, 12 hours and 24 hours post operatively.

Countries

India

Contacts

Public ContactDr Satish Kumar M N

Bangalore medical college and research institute

drsats007@gmail.com9916207210

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026