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A comparison of intravenous anaesthesia with gas based anaesthetic with respect to reliability of monitoring of spinal cord function during spine surgery.

Comparison of TIVA with Propofol versus Sevoflurane and Dexmedetomidine on reliability of intra-operative MEP monitoring in spine surgical patients having pre-operative paresis. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067564
Enrollment
34
Registered
2024-05-17
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Using Total Intravenous Anaesthesia with Propofol during spine surgeries: Patient will be given anaesthesia with Propofol based TIVA. During critical junctures of surgery, spinal cord i

Sponsors

Mathew George
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for spine surgeries who have pre-operative motor power of Grade 3-4 attributable to the surgical issue that is being addressed

Exclusion criteria

Exclusion criteria: Patients with extensive flaccid paralysis below the level of surgery. Patients with known hypersensitivity to any of the drugs included in the protocol.

Design outcomes

Primary

MeasureTime frame
Outcome is based on the intra-operative reliability of measured potentials calculated on basis of ratio of the number of muscles with reliable potentials to the number of muscles monitored. Timepoint: Measurements will be taken 30 minutes after the induction of anaesthesia and during critical junctures of surgery. Study ends after recovery from anaesthesia and neurological assessment is completed.

Secondary

MeasureTime frame
To compare intra-operative reliability of motor evoked potentials with respect to incidence of fresh post-op neurological deficitsTimepoint: Post-operative assessment of fresh neurological deficits will be done after reversal of anaesthesia & patient has awoken. Following neurological assessment the secondary outcome will also have been completed

Countries

India

Contacts

Public ContactShyama C Shyam Sunder

Amrita Institute of Medical Sciences

mathew.doc@gmail.com9447841795

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026