Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: HFNC flow of 40L/min for 3 minutes during apnoeic oxygenation.: During induction of general anaesthesia, preoxygenation will be done at 40 L/min flow rate using High Flow Nasal Cannula
Sponsors
Maulana Azad Medical College
Eligibility
Inclusion criteria
Inclusion criteria: ASA physical status I and II
Exclusion criteria
Exclusion criteria: Any known contraindication to HFNC: bleeding in nose or oropharynx, pre-existing nasal obstruction, greater than 50 percent of nares occluded by nasal prongs. Patients on oxygen therapy. Any underlying chronic or restrictive lung disease (kyphoscoliosis, burn contractures). Previous lung surgery. BMI greater than 35 kg per meter square. Planned for awake intubation or a difficult airway. Any contra-indication to continuous positive airway pressure (CPAP) treatment. Pregnant patients, autonomic neuropathy, history of gastro-esophageal reflux disease(GERD).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaO2 in both the groups.Timepoint: At the end of 3 minutes of apnoeic oxygenation | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean difference in PaO2 and PaCO2 levels in both groups (baseline, after 3 minutes of pre-oxygenation, after 3 minutes of apnoeic oxygenation) . End tidal oxygen (FETO2) and End tidal carbon dioxide (ETCO2) after securing a definitive airway and after 3 minutes. Percentage of population with hypoxemia (SpO2 less than 92%). Patient comfort during pre-oxygenation immediately before induction on a 5 point Likert scale.Timepoint: Baseline, after 3 minutes of pre-oxygenation, after 3 minutes of apnoeic oxygenation, after securing a definitive airway and after 3 minutes of securing a definitive airway. | — |
Countries
India
Contacts
Public ContactNitya Nyalakonda
Maulana Azad Medical College
Outcome results
None listed