Health Condition 1: N920- Excessive and frequent menstruation with regular cycle
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: All women visiting obstetrics and gynecology OPD in AIIMS Bibinaga with heavy menstrual bleeding without a structural cause.
Exclusion criteria
Exclusion criteria: 1) Samples displaying evidence of hyperplasia or atypia on microscopic evaluation. 2) Samples with tissue that are inadequate for further immunohistochemical evaluation 3) Patients with pelvic inflammatory disease or any other conditions affecting the immunity like autoimmune diseases. 4) Patients on immune modifying drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the alterations in the number of uterine natural killer cells, T cells and macrophages in the endometrial biopsy specimens of women with normal menstrual cycles and those with heavy menstrual bleeding.Timepoint: At the time of Endometrial biopsy. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the expression of immunohistochemistry in uterine natural killer cells, T cells and macrophages in the endometrial biopsy specimens of women with heavy menstrual bleeding and correlate this with the severity of clinical symptoms in patients with HMB.Timepoint: On histopathology slides after endometrial biopsy | — |
Countries
India
Contacts
Public ContactMishu Mangla
All India Institute of Medical Sciences
Outcome results
None listed