Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Effect of End tidal CO2 35-40 mm of Hg on MAC BAR of desflurane.: To see hemodynamic response of surgical incision at End-tidal CO2 35-45 mm of Hg.Dose of inhalational anesthetic desflu
Sponsors
Dr Sunita kumari
Eligibility
Inclusion criteria
Inclusion criteria: ASA 1 or 2 Patient undergoing elective Common Bile Duct exploration with skin incision longer than 10 cm
Exclusion criteria
Exclusion criteria: A history of Anesthetic allergy A history of cardiovascular or pulmonary disease Renal dysfunction A history of mental or neurological disease A history of Radiotherapy or chemotherapy Alcohol or drug abuse 7.Preoperative medication use that might influence sympathetic responses to surgical incision
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MAC- BAR of desflurane required to have no hemodynamics during surgical incision.Timepoint: Intraoperative period Dose of inhalational anesthetic desflurane will be increased by 0.25 MAC or decreased by 0.25 MAC based on the hemodynamic response at 1 and 2 minutes after skin incision during intraoperative period. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic response to skin incision BIS value Timepoint: Intraoperative period at the time of 1 minute & 2 minutes after surgical incision. | — |
Countries
India
Contacts
Public ContactSwati
Indira Gandhi Institute of Medical Sciences ,Patna
Outcome results
None listed