Health Condition 1: F172- Nicotine dependence
Conditions
Interventions
Intervention1: Nicotine Gum: Nicotine gum 2mg or 4mg
based on the amount of tobacco
use, Every 1-2 hours , Oromucosal
route(chew and keep between
the teeth and buccal mucosa),
for 10 weeks
Contro
Sponsors
National Drug Dependent Treatment Centre
Eligibility
Inclusion criteria
Inclusion criteria: Age 18 to 60 years Male Current (last 1 month) user of tobacco by smoking route Diagnosed with nicotine dependence, current use as per ICD-11 criteria Currently following up in NDDTC OPD for Opioid agonist maintenance treatment (Buprenorphine-Naloxone) with 80% medication dispensing Willing to participate in follow up at 4-6 weeks and 12-14 weeks
Exclusion criteria
Exclusion criteria: History of co-morbid psychiatric illnesses (as per clinical interview) Current (last 1 month)Dependence on drugs other than opioid and nicotine Current users of smokeless tobacco Has ever received tobacco cessation intervention (except simple advice from a health care professional) in the past 3 months Unwilling to give informed consent Contraindication for Nicotine replacement therapy (accelerated hypertension, post-myocardial infarction period (2 weeks), hypersensitivity to NRT) or Bupropion (Seizure episode, eating disorder)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| i. Biochemically confirmed seven-day point prevalence abstinence at 1- and 3-month follow-up ii. Reduction in smoking use as measured by self-reported amount of tobacco use(number of beedi or cigarettes) Timepoint: 1 month and 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| i. Continuous abstinence from smoking at 1- and 3-month follow-up (Complete abstinence beginning on the target quit date till the date of assessment) ii. Change in the stage of motivation Timepoint: 1 month and 3 months | — |
Countries
India
Contacts
Public ContactDr Sonali Jhanjee
National Drug Dependence Treatment Centre
Outcome results
None listed