Effectiveness Of Two Pain Relieving Drugs In Relieving Pain After Surgery For Removing The Gall Bladder

Comparison Of Analgesic Efficacy Of Intra-Operative Intravenous Nefopam Paracetamol Combination Versus Intravenous Tramadol Paracetamol Combination On Post Operative Analgesia Among Patients Posted For Laparoscopic Cholecystectomy Under General Anaesthesia “– Randomised Double Blinded Study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067462

Enrollment

Registered

2024-05-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K812- Acute cholecystitis with chronic cholecystitis

Interventions

Intervention1: ADMINISTRATION OF ANALGESICS: ADMINISTRATION OF ANALGESICS TO DECREASE POST OPERATIVE PAIN, ASSESSED BY VISUAL ANALOGUE SCORES (VAS) Intervention2: ADMINISTRATION OF ANALGESICS TO REDUC

Eligibility

Inclusion criteria

Inclusion criteria: 1.Aged 18-60yrs 2.American society of Anaesthesiologist (ASA ) physical status grade 1,2 3.Posted for elective and emergency laparoscopic cholecystectomy under General Anaesthesia(GA).

Exclusion criteria

Exclusion criteria: 1.Refusal to Enrol for the study 2.known allergy to study drug , 3.K/c/o epilepsy , psychiatry disorders , opioid dependence and 4.Patients on current use of analgesics 5.Laparoscopic surgery later converted into open technique

Design outcomes

Primary

Measure	Time frame
Reduction in VAS scores Expected to be better with Inj Nefopam Paracetamol combination than Tramadol paracetamol combination Timepoint: Assessment of Post-operative Pain using VAS scores at 0th min , 5mins , 15mins , 30mins , 1st hour , 2nd hour , 6th hour ,12 hours and 24th hour	—

Secondary

Measure	Time frame
To Compare The Consumption Of Rescue Analgesics In The First 24 Hours Of Post-Operative Period .Timepoint: First 24 hours	—

Countries

India

Contacts

Public ContactDr Basavaraj Padara

Department of Anaesthesia , S.Nijalingappa Medical College and HSK hospital , Bagalkot 587102

drbasupadara@gmail.com08762363790

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026