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Immediate effect of beetroot juice and grapefruit juice on blood pressure in hypertensive individuals

Immediate synergistic effect of beetroot and grapefruit juice on autonomic variables among hypertensive individuals - A comparative-randomized crossover study - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067461
Enrollment
15
Registered
2024-05-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10- Essential (primary) hypertension

Interventions

Intervention1: Grapefruit juice mixed with Beetroot juice: 70 mL of freshly prepared beetroot extract will be mixed with 250 mL of freshly prepared grapefruit extract and given to subjects. ( extracti

Sponsors

Dr Abhay sai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.With primary arterial hypertension (greater than 140 mmHg systolic and/ or greater than 90 mmHg diastolic blood pressure) 2.Under antihypertensive medication from their primary care physician or specialist at the time of the investigation. 3.Those who were willing to participate in the study

Exclusion criteria

Exclusion criteria: 1.Secondary hypertension 2.Two or more antihypertensive medications (resistant hypertension) 3.Severe psychiatric comorbidities 4.Coronary artery disease, myocardial infarction, pulmonary embolism, or stroke in the previous 3 months 5.Heart failure of NYHA stage 1 6.Renal failure of stage 2 or more (GFR less than 60mL/min/1.73m2) 7.Pregnancy or breastfeeding 8.Those who consumed beetroot or grapefruit in the last 4 days

Design outcomes

Primary

MeasureTime frame
Blood pressure, Heart rate variabilityTimepoint: Baseline and 30 mins, 1.5 hrs, 3 hrs, 4.5 hrs post intervention

Secondary

MeasureTime frame
immediate blood pressure changes during each of the juice consumptionTimepoint: baseline, 30 mins and one hr post intervention

Countries

India

Contacts

Public ContactDr Prashanth Shetty

Sri Dharmasthala Manjunatheshwara college of Naturopathy and Yogic sciences, Ujire

abhaysai2010@gmail.com9482052965

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026