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A study to Assess the Efficacy of Luteolin Gel as an Adjuvant Therapy in the Treatment of Periodontitis.

Efficacy of Local Drug Delivery of Luteolin Gel as an Adjuvant to Scaling and Root Planing in the Treatment of Chronic Periodontitis- A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067436
Enrollment
50
Registered
2024-05-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Luteolin Gel as an Adjuvant Therapy: Conventional Periodontal Therapy (Scaling and Root planing) will be done along with a one-time administration of 2% Luteolin Gel into the periodonta

Sponsors

JSS Academy of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Chronic periodontitis patients with minimum 20 remaining teeth. Periodontal pocket depth of minimum 4 – 6 mm and/ or CAL of 1 to 4 mm.

Exclusion criteria

Exclusion criteria: Unwilling patients. Systemic diseases having an impact on periodontium. Patients on medications known to affect the periodontium. Pregnant and lactating women. Smokers. Use of antibiotics within the Past 3 months. Periodontal therapy within the Past 6 months. Use of NSAID within the past 1 month. Subjects with oral mucosal lesions.

Design outcomes

Primary

MeasureTime frame
Periodontal Clinical parametersTimepoint: Baseline, 3 weeks post-treatment, 3 months post-treatment—

Secondary

MeasureTime frame
Estimation of IL-6 level in Gingival Crevicular FluidTimepoint: Baseline, 3 weeks post-treatment, 3 months post-treatment—

Countries

India

Contacts

Public ContactDr Premalatha BR

JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysore

sumanbv_72@yahoo.co.in9945551564

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026