Health Condition 1: Z00-Z99- Factors influencing health status and contact with health services
Conditions
Interventions
Intervention1: 0.05 mg/kg Neostigmine diluted to 10ml with normal saline: Will be administered intravenously at the time of reversal.
Control Intervention1: 10ml normal saline: Will be administered in
Sponsors
Dr Deepshikha Patangia
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged 20 to 60 years 2.American Society of Anesthesiology (ASA) physical status I and II 3.Scheduled for elective surgery under general anesthesia 4.Duration of surgery less than 3 hours.
Exclusion criteria
Exclusion criteria: 1.Patients with a BMI = 25 kg/m2 2.Pregnant or lactating women 3.With significant hepatic or renal dysfunction 4.With respiratory pathologies like COPD or is a chronic smoker 5.Family history of malignant hyperthermia 6.Any known allergy to one of the drugs used in this protocol or on recent use of sedatives, anti-depressants 7.Inability to assess muscle strength or TOF count (neuromuscular disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the time (in minutes) needed to achieve a TOF ratio of 0.9 after administering the study drug.Timepoint: 1. Preoperatively 2. Induction 3. Intubation 4. Extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To assess clinical parameters of postoperative recovery a. Sustained head lift(yes/no) b. Sustained hand grip(yes/no) c. Exhaled Tidal volume(in ml) 2. To assess length of Post Anesthesia Care Unit stay (in minutes) Timepoint: 1. Pre operatively 2. Induction 3. Intubation 4. Extubation | — |
Countries
India
Contacts
Public ContactDr. Amrita Panda
Kalinga Institute of Medical Sciences
Outcome results
None listed