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Evaluation of placenta by shear wave elastography

Comparative evaluation of placental Shear wave elastography and histopathology for the assessment of placental fibrosis in normal pregnancies and in those with placental syndromes: A Case-Control Study. - Shear-wave Elastography of placenta

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/05/067406
Enrollment
120
Registered
2024-05-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O09- Supervision of high risk pregnancy

Interventions

Control Intervention1: NIL: NIL

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women diagnosed with a placental syndromes like fetal growth restriction, pre-eclampsia, diabetes mellitus (gestational and overt), spontaneous preterm delivery, premature rupture of membranes, placental abruption, or intrauterine fetal demise.

Exclusion criteria

Exclusion criteria: 1. Iatrogenic preterm delivery 2. Cases with IUFD, are due to causes other than those, that can be attributed to placental abnormalities. 3. Posteriorly attached placenta 4. Patients with multiple pregnancy 5. Pregnancies with congenital anomalies in the fetus.

Design outcomes

Primary

MeasureTime frame
To assess the accuracy, sensitivity, and specificity of Shear wave elastography, for assessing placental stiffness/fibrosis in patients with placental syndromes taking placental histopathology as the standard.Timepoint: Within one week of delivery and after delivery—

Secondary

MeasureTime frame
3. To evaluate how placental stiffness as assessed by Shear wave elastography & placental fibrosis as assessed by histopathological examination, vary with maternal age, gravidity, parity, BMI, & area of interrogation within the placenta on stiffness measurements.Timepoint: At disease diagnosis, & within one week of delivery.;To find out whether changes in placental stiffness as assessed by Shear wave elastography correlate with disease severity in patients with placental syndromes.Timepoint: At disease diagnosis, & within one week of delivery.;To identify a threshold of placental stiffness, as measured by SWE, beyond which the chances of feto-maternal complications increase.Timepoint: SWE will be done twice, one at disease diagnosis, and second within one week of delivery.—

Countries

India

Contacts

Public ContactMishu Mangla

All India Institute of Medical Sciences

mishusingla83@gmail.com09988805850

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026