Comparing two ways to predict who will survive in the ICU: One uses a scoring system called APACHE IV score, while the other estimates Serum Hepcidin levels through a blood test

Comparison of Acute Physiology and Chronic Health Evaluation IV score and serum hepcidin levels as predictor of mortality in patients admitted to intensive care unit - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067373

Enrollment

Registered

2024-05-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: Serum hepcidin levels : To predict the mortality of patients admitted in Intensive Care Unit by estimating their Serum hepcidin level after 48 hours of admission Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 18 years, Below 65 years, Patient in ICU stay more than 48 hours

Exclusion criteria

Exclusion criteria: 1. Refusal to consent from patient’s relative 2. ICU stay less than 2 days (shift to ward or discharge within 2 days) 3. Burns 4. Head injury 5. Patients receiving chemotherapy/ having malignancy

Design outcomes

Primary

Measure	Time frame
Comparison of Acute Physiology and Chronic Health Evaluation IV score and serum hepcidin levels as predictor of mortality in patients admitted to intensive care unitTimepoint: APACHE IV score will be calculated within 24 hours of admission in ICU. Serum hepcidin level measured after 48 hours of admission in ICU.	—

Secondary

Measure	Time frame
Correlation of APACHE IV score with development of sepsis and length of stay in ICUTimepoint: APACHE IV score will be calculated within 24 hours of admission in ICU.;Correlation of serum hepcidin levels with development of sepsis and length of stay in ICUTimepoint: Serum hepcidin level will be measured after 48 hours of admission in ICU.;Correlation of SOFA score to predict the development of sepsisTimepoint: SOFA score calculated after 48 hours of admission and will be done every alternate days at a given designated time	—

Measure

Time frame

Correlation of APACHE IV score with development of sepsis and length of stay in ICUTimepoint: APACHE IV score will be calculated within 24 hours of admission in ICU.;Correlation of serum hepcidin levels with development of sepsis and length of stay in ICUTimepoint: Serum hepcidin level will be measured after 48 hours of admission in ICU.;Correlation of SOFA score to predict the development of sepsisTimepoint: SOFA score calculated after 48 hours of admission and will be done every alternate days at a given designated time

—

Countries

India

Contacts

Public ContactDr Anshu Palta

Government Medical College and Hospital, Sector 32B, Chandigarh

sanjeev_palta@yahoo.com9646121523

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026