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Efficacy of corticosteroid injection before removal of tooth.

Efficacy of submucosal and massetric methylprednisolone prior to impacted third molar surgery- A randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067285
Enrollment
76
Registered
2024-05-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth Health Condition 2: K011- Impacted teeth

Interventions

Intervention1: Submucosal methylprednisolone injection: Patients with impacted third molar with no medical comorbidities will be injected with submucosal methylprednisolone 40 mg/ml injection intraora

Sponsors

Priyanka Gajare
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients who are willing to participate in the study. 2. Healthy subjects (ASA Grade I and Grade II patients). 3. Patients in the age group of 21-40 years. 4. Patients with no contraindications to the drugs or anaesthetic used in the surgical protocol. 5. Patients with Moderate Difficulty index of impacted mandibular third molar as per Pederson Difficulty Index

Exclusion criteria

Exclusion criteria: 1. Patients not giving consent for participation in the study. 2. Immunocompromised patients. 3. Patients who are contraindicated to corticosteroids. 4. Diabetic patients 5. Pregnant or lactating patients. 6. Mentally challenged patients, those with severe systemic conditions, bone infections, osteomyelitis or osteoradionecrosis of jaw, any malignancy, cyst or tumor associated with the third molar.

Design outcomes

Primary

MeasureTime frame
Reduction in pain, swelling, trismus and evaluation of post operative complications and quality of lifeTimepoint: 1 day, 4 days, 1 week, 2 weeks

Secondary

MeasureTime frame
Not applicableTimepoint: Not applicable

Countries

India

Contacts

Public ContactPriyanka Gajare

Government Dental College and Hospital Mumbai

dr.kavitawadde@gmail.com9004799405

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026