Effect of topical recombinant human epidermal growth factor on chronic diabetic ulcer compared with conventional saline dressing

Effect of topical recombinant human epidermal growth factor on chronic diabetic ulcer compared with conventional saline dressing - Randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067239

Enrollment

100

Registered

2024-05-13

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Management of diabetic foot ulcer using recombinant human epidermal growth factor: The diabetic wound is debrided and application of recombinant human epidermal growth factor is done fo

Eligibility

Inclusion criteria

Inclusion criteria: Grade 1 and 2 wagners classification ulcer duration more than 3 weeks able to understand the merits and demerits of both the procedure and provide consent

Exclusion criteria

Exclusion criteria: Age less than 18 years and more than 80 years 2.Patient with cardiac disease,HIV,Hepatitis, pregnancy and critically ill patients 3.Chronic venous/Aretrial ulcers 4.Malignant ulcers 5.Anemia( <7gm/dl) 6.Known or Suspected osteomyelitis 7.Ulcer is less than 2cm.

Design outcomes

Primary

Measure	Time frame
To compare improvement in wound healing using recombinant human epidermal growth factor with conventional normal saline dressingTimepoint: 2 weeks	—

Secondary

Measure	Time frame
The reduction in wound size and improvement in healing by application of recombinant human epidermal growth factorTimepoint: 2 weeks	—

Countries

India

Contacts

Public ContactDr.A.Sneha Daffodil

Sri Manakula Vinayagar Medical college and hospital

gvmfhm@yahoo.co.in9443112296

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026