Health Condition 1: F05- Delirium due to known physiological condition
Conditions
Interventions
Intervention1: Melatonin: Melatonin 6mg will be given orally at night time for a total of 5 days
Control Intervention1: Melatonin: Melatonin 3mg will be given orally at night time for a total of 5 day
Sponsors
Vardhman Mahavir Medical College and Safdarjung Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Preserved oral/enteral intake within the first 48 hours of ICU admission. 2. Patients requiring an ICU stay of at least 5 days. 3. Richmond Agitation Sedation Scale (RASS) score within + 2 or - 2 on admission
Exclusion criteria
Exclusion criteria: 1. Hemodynamically unstable patients or on vasopressor support 2. Patients on psychotropic medications or having known psychiatric illness 3. Patients with debilitating neurological diseases and low GCS less than 10 on admission 4. Pregnant patients 5. Patient with known or suspected allergy to melatonin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of deliriumTimepoint: Twice a day once at 9 am and after giving the melatonin tablet at 9pm for a period of 5 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare length of Intensive Care Unit stay in 2 study groups. 2. To compare the incidence of headache, dizziness and day-time sleepiness between the two study groups.Timepoint: At the end of their hospital stay | — |
Countries
India
Contacts
Public ContactDr Santvana Kohli
Vardhman Mahavir Medical College and Safdarjung Hospital
Outcome results
None listed