Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Individuals of both genders aged between 18 and 60 years, with a weight falling within the range of 40 to 80 kg with physical status American Society of Anaesthesiologists (ASA) I and II, undergoing elective abdominal surgery under general anaesthesia will be included.
Exclusion criteria
Exclusion criteria: 1) Long term use of sedative drugs (benzodiazepines, barbiturates), 2) Anticipated difficult airway, 3) Those who received alpha2 agonists preoperatively, 4) Patients who were transferred to open surgery during the operation were excluded from the final analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will include severity of cough at extubation assessed by 4 point cough scaleTimepoint: 0 minutes, 2 minutes, 5 minutes, 15 minutes, 30 minutes post extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Monitoring of hemodynamic parametersTimepoint: 5 min before anaesthesia(T0), immediately after administration of dexmedetomidine(T1), 5 min after DEXMEDETOMIDINE(T2), 10 min after DEXMEDETOMIDINE(T3), at end of surgery(T4), at awareness(T5), at extubation(T6), 2 min after extubation(T7), 5 min after extubation(T8), 15 min after extubation(T9), 30 min after extubation(T10) | — |
Countries
India
Contacts
Dr S N Medical college