Comparison of satranidazole and hyaluronic acid gels in addition to scaling and root planing for treatment of stage I and stage II periodontitis

Clinical and microbiological efficacy of 3% satranidazole and 0.8% hyaluronic acid oral insitu gels as an adjunct to scaling and root planing in the treatment of stage 1 and stage 2 periodontitis. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067068

Enrollment

Registered

2024-05-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: 3% satranidazole oral insitu gels: After scaling and root planing oral insitu gels are placed in the periodontal pocket Control Intervention1: 0.8% hyaluronic acid oral insitu gel: Afte

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age group of 35-55 years of both the gender. 2.Apparently Healthy individuals 3.Subjects with Stage I (Interdental CAL – 1 to 2 mm, radiographic boneloss less than 15% of coronal third, maximum probing depth less than or equal to 4mm) and Stage II periodontitis (Interdental CAL – 3 to 4mm, radiographic bone loss 15- 33% of coronal third, maximum probing depth less than or equal to 5mm) 4.Subjects who are willing to give informed consent.

Exclusion criteria

Exclusion criteria: 1. Subjects using any form of tobacco. 2. History of previous antibiotic therapy within the past 3 months 3. Subjects who has history of drug allergy. 4. Pregnant woman and Lactating mothers. 5. Subjects with Stage III and Stage IV periodontitis.

Design outcomes

Primary

Measure	Time frame
Reduction in probing depth ,gain in clinical attachment levels and bacterial countTimepoint: Baseline 1 month 3 months	—

Secondary

Measure	Time frame
Decreased plaque and gingival scoreTimepoint: Baseline 1 month 3 months	—

Countries

India

Contacts

Public ContactDr Boyapati ramanarayana

Sibar institute of dental sciences

dr.ramanarayana@gmail.com9490144365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026