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To study the beneficial effects of dexmedetomidine drug by adding to lignocaine nebulization in patients undergoing general anesthesia for better outcome.

Comparison of Lignocaine Nebulization versus Lignocaine with Dexmedetomidine Nebulization for Awake Fiberoptic Intubation: A Double Blind Randomized Controlled Trial - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067063
Enrollment
80
Registered
2024-05-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: V299- Motorcycle rider (driver) (passenger) injured in unspecified traffic accident

Interventions

Intervention1: Nebulization Lignocaine + Dexmedetomidine: 4%Lignocaine 5ml + Dexmedetomidine 1.5mcg/kg diluted with normal saline upto 7 ml given via nebulization only once for 20minutes Contr

Sponsors

Dr T G KHAAR MUGILAN
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients scheduled to undergo elective surgeries under general anesthesia. 2.Patients of ASA physical status I&II. 3.Patients of either sex. 4.Age 18 to 60 years. 5.Body Mass Index 18 to 35 kg/m2.

Exclusion criteria

Exclusion criteria: 1.Patients with difficult airway. 2.Pregnant/Lactating Women. 3.Severe mental illness, or Cognitive dysfunction (unable to communicate or cooperate) 4.Patients with thrombocytopenia or coagulopathy. 5.Patients with nasal polyps, history of previous nasal surgery/nasal trauma. 6.Patients allergic to the drugs involved in the study. 7.Patients refusal for participation in the study.

Design outcomes

Primary

MeasureTime frame
To Estimate and compare mean intubation time in Lignocaine Nebulization and Lignocaine with Dexmedetomidine Nebulization for Awake Fiberoptic IntubationTimepoint: Seconds (during intubation)

Secondary

MeasureTime frame
1.To Estimate and compare hemodynamic changes and level of sedation in both groups 2.To Assess and compare intubation condition, vocal cord position, cough severity, patient tolerance and postoperative patient satisfaction in both groupsTimepoint: 1,2,3,5,10,20Minutes

Countries

India

Contacts

Public ContactDr C PRASATH

Sri Manakula Vinayagar Medical College and Hospital

drpathin2@gmail.com9787740890

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026