Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Conditions
Interventions
Intervention1: Group B :1:4 Ketofol Group: Group B admixture will contain 25mg of ketamine and 100mg propofol diluted up to 20 ml in a single syringe
In the OT, vital monitors will be attached and bas
Sponsors
UCMS and GTB Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1)Consenting patients aged 18-65 years posted for expolrative laparotomy under general anaesthesia 2)Hemodynamically stable patients
Exclusion criteria
Exclusion criteria: 1)Patient with heart block on peri operative ECG 2)Patient with heart rate less than 50bpm 3)Hemodynamically unstable patient with mean arterial pressure less than 60mmHg 4)Patient on inotropes 5)Patient with signs and symptoms of raised intracranial tension 6)Patient with known allergy to any of the drug used
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare incidence of hypotension between groups A and BTimepoint: Baseline 0 minute | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) HR, SBP, DBP immediately post induction, 2) HR, SBP, DBP immediately post intubation, 3) Consumption of norepinephrine till 1 hour post intubation, 4) Intubating conditions during intubation 5) HR and MAP at the end of 5 minutes, 10 minutes 15 minutes, 20 minutes, 30 minutes and 1 hour, Timepoint: 1)post induction 2)at the time of intubation 3)post intubation 4)5,10,15,20,30,60 minutes post intubation. | — |
Countries
India
Contacts
Public ContactDr Suhani Agarwal
UCMS and GTB Hospital
Outcome results
None listed