To study the effect of Leg compression by air filled device on post anaesthesia decrease in blood pressure in head injury patients undergoing surgery on head to remove bone and decrease pressure by the injured brain

Effect of Pneumatic leg Compression on Post Induction hypotension in Adult Patients undergoing decompressive craniotomy surgeries in isolated Traumatic Brain Injury patients: A Randomised Controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067020

Enrollment

Registered

2024-05-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S062- Diffuse traumatic brain injury

Interventions

Intervention1: Pneumatic compression of Leg (calf muscles): The pneumatic compression device will be attached prior to anaesthesia induction. In all patients of PC Group, the pneumatic compression dev

Eligibility

Inclusion criteria

Inclusion criteria: 90 ASA I, II and III patients aged between 18-65 years having isolated severe traumatic brain injury i.e midline shift of â?¥5mm and effacement of cisterns in CT scan, scheduled for decompressive craniotomy will be enrolled in this study.

Exclusion criteria

Exclusion criteria: Uncontrolled hypertension and coronary artery disease, history of DVT, patient refusal, poor ejection fraction

Design outcomes

Primary

Measure	Time frame
To compare the incidence of â??post induction hypotensionâ?? after induction in the patients undergoing â??decompressive craniotomy surgery ? between the pneumatic and control groupsTimepoint: 20 minutes after induction of Anaesthesia	—

Secondary

Measure	Time frame
â?¢ Number of hypotensive episodes in first 20 mins after induction and post decompression craniotomy till end of surgery.Timepoint: First 20 min after anaesthesia induction and decompressive craniotomy procedure;Use of vasopressors and, intravenous fluids etc. in first 20 minute and thereafter during surgery.Timepoint: First 20 minutes after anaesthesia induction and then throughout the duration of surgery;Arterial blood gas changes between the baseline, 20 minutes post induction and at the end of the surgery in terms of base deficit, lactate and p/f ratio.Timepoint: Baseline before anaesthesia induction, 20 minutes post induction of anaesthesia and at the end of surgery.;Observe the incidence of complications/side effects of the use of pneumatic compression deviceTimepoint: Every 8 hours till 72 hours post surgery	—

Measure

Time frame

â?¢ Number of hypotensive episodes in first 20 mins after induction and post decompression craniotomy till end of surgery.Timepoint: First 20 min after anaesthesia induction and decompressive craniotomy procedure;Use of vasopressors and, intravenous fluids etc. in first 20 minute and thereafter during surgery.Timepoint: First 20 minutes after anaesthesia induction and then throughout the duration of surgery;Arterial blood gas changes between the baseline, 20 minutes post induction and at the end of the surgery in terms of base deficit, lactate and p/f ratio.Timepoint: Baseline before anaesthesia induction, 20 minutes post induction of anaesthesia and at the end of surgery.;Observe the incidence of complications/side effects of the use of pneumatic compression deviceTimepoint: Every 8 hours till 72 hours post surgery

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Countries

India

Contacts

Public ContactANKUR LUTHRA

PGIMER, Chandigarh

zazzydude979@gmail.com919868057732

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026