Flupirtine as addition to pain relief for patients undergoing thoraco-lumbar spine surgeries

Efficacy of flupirtine as add on therapy to standard post operative pain management in patients undergoing thoraco-lumbar spine surgeries- A randomized control study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067016

Enrollment

Registered

2024-05-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Flupirtine: Flupitine as add on therapy to standard post operative pain management Control Intervention1: Standard post operative pain management: standard post operative pain managemen

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anaesthesiologists physical status 1,2 and 3 patients undergoing elective thoro-lumbar procedure lasting for 3-6 hours under general anaesthesia

Exclusion criteria

Exclusion criteria: Refusal to consent for proposed study BMI more than 30 kg/m2 Hypersensitivity to study drug Hepatobiliary disorders/Chronic alcoholism/Neuromuscular disorders

Design outcomes

Primary

Measure	Time frame
Effectiveness of Flupirtine in reducing postoperative painTimepoint: 0,4,8,12,24,36,48,60,72 hours	—

Secondary

Measure	Time frame
To compare length of stay in hospitalTimepoint: Day 0, day 1, day 2, day 3;To compare the ambulation on cumulated ambulation scoreTimepoint: Day 0, day 1, day 2, day 3;To compare the groups for side effects like nausea/vomiting, Abdominal discomfort,bloating,diarrhea, mood changes(hallucinations,depression)Timepoint: Day 0, day 1, day 2, day 3	—

Countries

India

Contacts

Public ContactDr Geetha L

M S Ramaiah Medical College

geetha4kiran@yahoo.in9611897899

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026