To Compare The Effectiveness Of Inferior Alveolar Nerve Block For Pain Management During Root Canal Treatment Using Lignocaine With Articaine And Cryotherapy as an adjunct

To Evaluate And Compare The Efficacy Of Inferior Alveolar Nerve Block In Symptomatic Irreversible Pulpitis Cases Using Lignocaine With Articaine And Cryotherapy As An Adjunct, In Pain Reduction During Endodontic Procedures - A Clinical Trial - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/066981

Enrollment

150

Registered

2024-05-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: endo ice: endo ice (ethyl chloride and butane) Intervention2: standard Inferior alveolar nerve block with lignocaine hydrochloride and supplementary buccal infiltration with articain

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with symptomatic irreversible pulpitis (SIP) planned for endodontic treatment in mandibular molars. Patients within the age group of 20–50 years. Teeth responding to cold and EPT test with lingering pain sensation for more than 30 sec. Preoperative NRS score greater than 4 (Moderate to severe pain). Patient consenting to be a part of this study.

Exclusion criteria

Exclusion criteria: Patients not willing to participate in the study. Age less than 20 years and more than 50 years. Patients allergic to lignocaine or articaine. Immature young permanent teeth. Teeth that do not respond to vitality tests (Cold test and EPT). Acute and chronic alveolar abscess. Calcified pulp chamber and root canals. Previously filled root canals. Periodontally compromised teeth. Medically compromised patients. Patients with a history of intake of analgesics, steroids or antibiotics in the recent past 48 h.

Design outcomes

Primary

Measure	Time frame
To evaluate and compare the efficacy of IANB with 2% lignocaine hydrochloride , lignocaine with articaine and cryotherapy as an adjunct in symptomatic irreversible pulpitis cases.Timepoint: The patient will be asked to quantify the pain at 3 intervals i.e pre operative, during access opening and immediately after pulp extirpation	—

Secondary

Measure	Time frame
To compare the efficacy of IANB with 2% lignocaine hydrochloride , lignocaine with articaine and cryotherapy as an adjunct in symptomatic irreversible pulpitis cases.Timepoint: The patient will be asked to quantify the pain at 3 intervals i.e pre operative, during access opening and immediately after pulp extirpation	—

Countries

India

Contacts

Public ContactRidha Iqbal

I.T.S Dental College Hospital And Research Centre

dr.manjukumari.dntl.gn@its.edu.in9811056881

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026