Health Condition 1: K801- Calculus of gallbladder with othercholecystitis
Conditions
Interventions
Intervention1: to study effect on peri-operative hemodynamics and post-operative analgesia in patients undergoing laparoscopic cholecystectomy: Intravenous paracetamol or intravenous dexmedetomidine w
Sponsors
Pt B D Sharma PGIMS Rohtak
Eligibility
Inclusion criteria
Inclusion criteria: The study will include 90 patients of either sex. age 18–60 years, belonging to American Society of Anesthesiologists (ASA) physical status of I-II with scheduled for elective laparoscopic cholecystectomy under general anaesthesia and will be assigned to two groups
Exclusion criteria
Exclusion criteria: Obesity Already receiving beta blocker or alpha-2 agonists History of allergy to test drug History of hypertension with or without medication History of cardiopulmonary disease History of hepatic and renal dysfunction History of psychological disorders History of alcohol and drug abuse Receiving opioid analgesics during last 24 hours before surgery Heart Rate less than 50bpm Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the effectiveness of paracetamol & dexmedetomidine on peri-operative hemodynamics and postoperative analgesia in patients undergoing laparoscopic cholecystectomy under general anaesthesia .Timepoint: First of all, spo2, NIBP, and pulse rate will be recorded at baseline before and after the administration of drugs and pain score will be assessed at 1/2, 2, 4, and 6 hours in patients undergoing laparoscopic cholecystectomy under general anaesthesia . | — |
Secondary
| Measure | Time frame |
|---|---|
| All the vital parameters (spo2, pulse rate, NIBP, & pain score) will be assessed.Timepoint: At baseline, just before & after the administration of drugs & pain score at 1/2, 2, 4 & 6 hours post-operatively | — |
Countries
India
Contacts
Public ContactDr Navdeep Singh
Pt B.D. Sharma PGIMS Rohtak
Outcome results
None listed