Comparing the total duration of analgesia when dexamethasone and dexmedetomidine are added to bupivacaine in spinal anaesthesia.

A prospective randomized comparative study to evaluate efficacy of intrathecal dexamethasone and dexmedetomidine added as adjuvant to bupivacaine in pregnant patient posted for elective LSCS. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/066941

Enrollment

Registered

2024-05-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O754- Other complications of obstetric surgery and procedures

Interventions

Intervention1: RANDOMISED CONTROLL TRIAL: Comparison of postoperative analgesia between bupivacaine (10 mg) with dexmedetomidine (10 mcg) and bupivacaine (10mg) with dexamethasone (8 mg) in spinal ana

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grades 1 & 2 BMI 20 TO 30 No history of bleeding tendency No previous uterine operation except cesarian section Living foetus

Exclusion criteria

Exclusion criteria: ASA 3 & 4 Patient having systemic disease Severe coronary insufficiency BMI > 30 The patient requires repeat intrathecal bupivacaine.

Design outcomes

Primary

Measure	Time frame
The duration of postoperative analgesia is longer with dexamethasone as an adjuvant with bupivacaine.Timepoint: The time duration will be noted for the first rescue analgesia.	—

Secondary

Measure	Time frame
Intraoperative hemodynamics Prevention of perioperative shivering comparative study of sedation Timepoint: 2 Years	—

Countries

India

Contacts

Public ContactSamarpan Patel

DATTA MEGHE INSTITUTE OF HIGHER EDUCATION AND RESEARCH

doctorchandak@gmail.com9422903551

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026