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Comparison of Levobupivacaine (0.5%) and Ropivacaine (0.75%) in Lower Limb Surgeries under Spinal Anaesthesia

A Randomised comparative study between hyperbaric Levobupivacaine(0.5%) and hyperbaric Ropivacaine(0.75%) in lower limb surgeries under spinal Anaesthesia. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/066935
Enrollment
80
Registered
2024-05-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: X58- Exposure to other specified factors

Interventions

Intervention1: Subarachnoid Block Using Spinal Needle: For Group A: Hyperbaric Levobupivacaine (3ml) and for Group B: Hyperbaric Ropivacaine (3ml) will be given under Aseptic conditions using Spinal N

Sponsors

LLRM Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA GRADE I and II Age between 18 to 65 years Patients undergoing lower limb Surgeries

Exclusion criteria

Exclusion criteria: Patient Refusal Infection at the Injection Site Coagulopathy Increased Intracranial Pressure Known Allergy or Hypersensitivity to Local Anaesthetic Agents

Design outcomes

Primary

MeasureTime frame
The primary outcome is to study the efficacy of the drug based on Duration of motor blockade , assessed by Modified Bromage scale.Timepoint: Baseline vitals will be noted. After Spinal anesthesia, Haemodynamic parameters ( SBP,DBP,MAP,HR), Loss of sensory and motor function will be noted every 1 minute for first 5 minutes, every 2 minutes for next 10 minutes, every 5 minutes for next 25 minutes and then every 30 minutes till regression of block.

Secondary

MeasureTime frame
1.To compare and Evaluate Onset of sensory block in both the groups 2.To compare and Evaluate Onset of motor block in both the groups 3.To compare and Evaluate Duration of Motor block in both the groups 4.To compare and Evaluate time of first rescue Analgesia in both the groups 5.To compare hemodynamic changes if any 6.Complications if any in both the groupsTimepoint: Baseline vitals will be noted. After Spinal anesthesia, Haemodynamic parameters ( SBP,DBP,MAP,HR), Loss of sensory and motor function will be noted every 1 minute for first 5 minutes, every 2 minutes for next 10 minutes, every 5 minutes for next 25 minutes and then every 30 minutes till regression of block.

Countries

India

Contacts

Public ContactDr Neelam Singh

Llrm medical college

v.tiwari1234@gmail.com7830666616

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026