Comparison of a continuous drip or new method of giving several small injections, of the medicine, phenylephrine, to prevent fall in BP, during caesarean delivery

Comparison of a modified regimen of prophylactic phenylephrine boluses versus variable rate infusion during elective caesarean section under spinal anaesthesia: a non-inferiority randomised double-blind study - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/066927

Enrollment

Registered

2024-05-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Bolus Group: Prophylactic bolus of 100mcg phenylephrine will be given after spinal block and repeat doses will be given to maintain systolic blood pressure near baseline values till the

Eligibility

Inclusion criteria

Inclusion criteria: Healthy mothers with term, uncomplicated, singleton pregnancy scheduled to undergo elective caesarean section under spinal anaesthesia

Exclusion criteria

Exclusion criteria: Maternal complications e.g., pre-eclampsia, cardiovascular disease, cerebrovascular disease, Multiple gestation, Placental complications, Known fetal abnormality, absolute or relative contra-indications for spinal anaesthesia

Design outcomes

Primary

Measure	Time frame
Number of physician interventionsTimepoint: delivery of baby	—

Secondary

Measure	Time frame
1. Phenylephrine requirements 2. Number of episodes of hypotension, reactive hypertension, bradycardia or arrhythmias 3. Umbilical arterial and venous blood gas analysis 4. Apgar scores at 1 and 5 minutes 5. Incidence of nausea, vomiting, dizziness, or any other maternal complication Timepoint: Delivery of baby	—

Countries

India

Contacts

Public ContactDr Sorabh Anchal

University College Of Medical Sciences and Guru Teg Bahadur Hospital

medhamohta@gmail.com9868399626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026