Health Condition 1: C719- Malignant neoplasm of brain, unspecified Health Condition 2: C719- Malignant neoplasm of brain, unspecified
Conditions
Interventions
Intervention1: Eleveld plus Opioid model: The HP TCI pump (Medcaptain Medical Technology) will be set for the Eleveld plus Opioid model with an effect-site concentration of 3 mcg/ml.The time required
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: All individuals of 18-60 years of age undergoing elective craniotomy for brain tumors in JIPMER, belonging to ASA 1 and 2 planned for general anesthesia.
Exclusion criteria
Exclusion criteria: Contraindications to the use of propofol. Patients who had received propofol in the past 24 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the total amount of propofol used in Eleveld+Opioid model and Schnider model.Timepoint: baseline, immediately after induction, minute 1,2,3,4,5, 10, 15, 20, 25, 30, 60, 90, 120, 150, 180, 210, 240 from induction | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the time for the loss of eye-lash reflex & for the loss of verbal response. To compare the time to achieve the desired effect site concentration. To compare the time to reach the BIS level of 50. To compare the intraoperative hemodynamics. To compare the intraoperative brain relaxation. To compare the recovery characteristics Timepoint: baseline, immediately after induction, Minute 1, 2, 3,4,5,10,15, 20, 25, 30, 60, 90, 120, 150, 180, 210, 240 from induction | — |
Countries
India
Contacts
Public ContactDr Adinarayanan S
Jawaharlal Institute of Postgraduate Medical Education and Research
Outcome results
None listed