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Camparision between Dexmedetomidine and Fentanyl in supressing hemodynamic responses during Laryngoscopy and Intubation.

Comparison between Dexmedetomidine and Fentanyl in attenuation of hemodynamic responses during Laryngoscopy and Intubation – A Prospective Randomized Controlled Study - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/066906
Enrollment
66
Registered
2024-05-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J039- Acute tonsillitis, unspecified Health Condition 2: H701- Chronic mastoiditis Health Condition 3: J349- Unspecified disorder of nose and nasal sinuses

Interventions

Control Intervention1: DEXMEDETOMIDINE: Patients under trail are given 0.5micrograms/kg of Dexmedetomidine 15minutes before intubation and observing supressor hemodynamic responses of Dexmedetomidine

Sponsors

G AnilKumar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA Physical status I and II patients. 2)Weight 50 to 100kg. 3)Airway of Mallampati Grade I and II

Exclusion criteria

Exclusion criteria: 1)Patients with severe hypertension, ischemic heart disease, arrhythmias, on beta blockers, atrioventricular dysfunction. 2)Pregnants, full stomach patients and emergency surgeries. 3)Patients in which duration of laryngoscopy took greater than 30seconds.

Design outcomes

Primary

MeasureTime frame
camparing changes in Heart Rate.Timepoint: Compare which among these drugs Dexmedetomidine 0.5mcg/kg and Fentanyl 2mcg/kg in attenuating stress response like Heart Rate to laryngoscopy and endotracheal intubation is best.

Secondary

MeasureTime frame
1)Changes in Other hemodynamic parameters like SBP, DBP, MAP, SPO2 during the process 2)To look for any adverse effects during the interventions.Timepoint: 1)Changes in Other hemodynamic parameters like SBP, DBP, MAP, SPO2 at 1minute, 3minutes, 5minutes, 7minutes & 10 minutes after intubation 2)To look for any adverse effects during the interventions

Countries

India

Contacts

Public ContactDr Mallanna BP

District Hospital Bellary

drmallanna@yahoo.com9845652555

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026