Health Condition 1: K829- Disease of gallbladder, unspecified
Conditions
Interventions
Intervention1: ALPRAZOLAM
Dose-0.5mg,
Frequency- single tablet 3 hours prior to surgery.
Route- Oral
Time duration - 12 months: Anxiety level, amnesia and degree of sedation will recorded at the tim
Sponsors
Sanjay Gandhi Post Graduate Institute of Medical sciences Lucknow Uttar pradesh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient giving written consent. 2. Patients belonging to ASA grade I and II. 3. All genders 4. Normal BMI(18.5-25) subjects. 5. Patients in the age group (18-60years) undergoing elective laparoscopic cholecystectomy.
Exclusion criteria
Exclusion criteria: 1. Patients not giving consent. 2. ASA grade III and IV. 3. Emergency surgeries. 4. Patient who had taken analgesic, sedative, antidepressant, and on antiepileptic drugs were excluded. 6. Patients with psychiatry illness will be excluded. 5. Patients with anticipated difficult airway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Objective – 1.Comparison of Alprazolam and Lorazepam in terms of anxiolysis by Hamilton anxiety rating scale (HAM-A). 2. Comparison of level of amnesia by MMSE score at time T1 and T2. Timepoint: At the time of giving premedication in the ward 3 hours prior to GA (T1), in the preoperative ward before shifting the patient to the operation theatre (T2) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objectives – (i)Comparison of level of sedation by using Ramsey sedation score at time T1 & T2Timepoint: At the time of giving premedication in the ward 3 hours prior to GA (T1), in the preoperative ward before shifting the patient to the operation theatre (T2) | — |
Countries
India
Contacts
Public ContactDr Vipiendra Singh Solanki
Sanjay Gandhi Post Graduate Institute of Medical sciences, Lucknow, Uttar pradesh.
Outcome results
None listed