Skip to content

Efficacy of desidustat in erythropoietin hyporesponsiveness among CKD patients

A comparative analysis of erythropoietin alpha and erythropoietin alpha with desidustat in the management of anemia during hemodialysis a randomized study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/066867
Enrollment
44
Registered
2024-05-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: Desidustat as a add on therapy with erythropoietin alpha as a treatment group: The treatment protocol of desidustat was 50 mg BD for morning and night for weekly thrice an alternate day

Sponsors

Arivazhagan S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ESRD patients on maintenance hemodialysis with anemia (hemoglobin level below 8g/dl) and receiving erythropoietin alpha and iron injection.

Exclusion criteria

Exclusion criteria: Patient with red blood cell transfusion (within 4 weeks) History of renal transplantation Previous or concurrent cancer Pregnancy and lactation

Design outcomes

Primary

MeasureTime frame
Improvement in the hemoglobin level in hyporesponsive state The adjunct therapy will be better when compared with control treatment Can able to assess the safety of the treatmentTimepoint: Hemoglobin Hematocrit The hemoglobin and hematocrit value follow up to the baseline, after 4th week, 8th week and 12th week

Secondary

MeasureTime frame
To reduce the number of hospital staysTimepoint: Number of hospital stay The hospital stay outcome calculated based on admission & discharge of patient (inpatient hospital days). in that days between the admission & discharge are used to identify the hospital stays

Countries

India

Contacts

Public ContactArivazhagan S

PSG college of pharmacy

subadradevij@psgpharma.ac.in8903476740

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026