A Study to compare two ways of deciding when to give blood transfusions during liver transplant to recipient which tests if Thromboelastography(Test 1) or Rotational thromboelastometry (Test 2)is better and the total amount of blood transfused between two groups will be compared.

Thromboelastography versus Rotational Thromboelastometry Guided Blood Transfusion in Living Donor Liver Transplantation - A Randomised Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/066783

Enrollment

Registered

2024-05-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K746- Other and unspecified cirrhosis ofliver

Interventions

Intervention1: ROTEM Test: ROTEM Intraoperatively during baseline, dissection, anhepatic and post reperfusion Postoperatively till day 3 Control Intervention1: TEG test: Intraoperatively baseline, dis

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients undergoing living donor liver transplant at our institute.

Exclusion criteria

Exclusion criteria: 1)Acute liver failure patients, Acute on chronic liver failure patients 2) Pediatric patients 3)Retransplantation in a patient previously randomized in this trial 4) Without informed consent 5) Patients with known coagulation factor deficiencies.

Design outcomes

Primary

Measure	Time frame
Total PRBCs transfused between two groups.Timepoint: Baseline, dissection phase, anhepatic phase, post reperfusion and postoperative day 1 ,2 and 3	—

Secondary

Measure	Time frame
1 To compare the amount of FFP,Cryoprecipitate & platelets transfused between both groups 2.To compare the changes in coagulation during different stages of liver transplant between the two groups 3. To compare the duration of mechanical ventilationTimepoint: Baseline Dissection phase Anhepatic phase Post reperfusion Postoperative day 1, 2 & 3	—

Countries

India

Contacts

Public ContactDr Gaurav Sindwani

Institute Of Liver and Biliary Sciences (ILBS)

drsindwani25@gmail.com8728089898

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026