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Effect of non steroidal anti-inflammatory eye drop(nepafenac) on eye(choroidal thickness) of diabetic patients without retinopathy (an end organ damage affecting eye) following cataract surgery

Impact Of 0.1% nepafenac on macular and choroidal thickness after uncomplicated Phacoemulsification surgery - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/066781
Enrollment
50
Registered
2024-05-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H309- Unspecified chorioretinal inflammation

Interventions

Intervention1: Nepafenac Group: On postoperative antibiotic steroid combination eye drops along with topical nepafenac for 1 month following cataract surgery Control Intervention1: Control group: On

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diabetic patients with no clinical evidence of diabetic retinopathy who have senile immature cataract (gr 2, gr 3) scheduled to undergo cataract extraction and posterior chamber Intra-ocular lens implantation

Exclusion criteria

Exclusion criteria: 1. Anterior segment pathology (corneal opacities, PEX, dense cataract) 2. Posterior segment pathology (DR, ARMD, retinal vascular diseases, uveitis) 3. Intra & Postoperative complications(TASS, raised IOP) 4.History of chronic oral/topical medication, intraocular surgery, ocular trauma.

Design outcomes

Primary

MeasureTime frame
Choroidal thickness measurements at 5 points (sub-foveal, 500µm temporal, nasal, superior & inferior to fovea) measured using EDI-OCTTimepoint: Choroidal thickness measurements at 5 points using EDI-OCT on preoperative day, post operative 1 week and post op 1 month—

Secondary

MeasureTime frame
Compare subfoveal choroidal thickness at 3 months post op with initial pre op readingTimepoint: 3 months—

Countries

India

Contacts

Public ContactDr Jaya Kaushik

Command Hospital(Central command), Lucknow

arnavjaya@gmail.com8390010094

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026