A clinical trial to study the effects of 1064 nm Q Switched Nd-YAG laser and glycolic acid peel in patients with macular amyloidosis

A comparative study on the efficacy and dermoscopic changes in 1064 nm Q Switched Nd-YAG laser versus glycolic acid peel in Macular Amyloidosis - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/066757

Enrollment

Registered

2024-05-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E854- Organ-limited amyloidosis

Interventions

Intervention1: 1064 nm Q switched Nd - YAG laser: For Q-switched Nd-YAG laser, IDS Q10 will be used. Only one group of patients, randomly assigned (QS Nd-YAG group) will be irradiated. The laser param

second peel, 3 min

third peel, 4 min

and fourth peel, 5 min

separated by 1 month intervals). The peel will be terminated by the dilutional effect of washing with cold water-soaked gauze pads in the same sequence as the application. The endpoint of the treatmen

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged =18 years of either sex, Patients with macular amyloidosis,Patients who are not on any topical/oral/laser therapy for last 01 month, Patients with written informed consent by self or by guardian

Exclusion criteria

Exclusion criteria: Patient with history of any treatment for macular amyloidosis in last 01 month, Pregnant females, Photosensitive dermatoses, Patients with known hypersensitivity to chemical peels, Patients with unrealistic expectations, Patients will be dropped from the study if any adverse effect noticed after test patch

Design outcomes

Primary

Measure	Time frame
Color score will be used before and 1 month after the treatment in both the groupsTimepoint: 6 months	—

Secondary

Measure	Time frame
Dermoscopic findingsTimepoint: 6 months;Subjective improvementTimepoint: 6 months;VAS (Visual Analogue Scale) - Will be done 1 month after completion of treatmentTimepoint: 6 months	—

Countries

India

Contacts

Public ContactGulshan Kumar Sirohi

Command Hospital Air Force Bangalore

debdeep5000@gmail.com8811851830

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026