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A study to see the effect of calcium and vitamin D supplementation on the progression of dengue fever to dengue shock syndrome and dengue hemorrhagic fever,

A randomized placebo controlled study evaluating the effect of calcium and vitamin D supplementation on the progression of dengue fever to dengue shock syndrome and dengue hemorrhagic fever - nil

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/066756
Enrollment
120
Registered
2024-05-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A90- Dengue fever [classical dengue]

Interventions

Intervention1: Calcium supplement group: Calcium carbonate 500mg 2 times a day for 15 days Intervention2: Vitamin D group: Capsules Vitamin D 4000 unit once daily for 15 days Control Intervention1: Pl

Sponsors

MILIND RAJ NAGVANSHI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient with acute dengue fever confirmed by lab investigations , all patients wiling to give informed consent, all acute dengue fever patient admitted to medicine wards /CCW/ICU at jnmch

Exclusion criteria

Exclusion criteria: Age more than 60 yr and pregnant females, patient presenting with dengue shock syndrome and dengue hemorrhagic fever, diagnosed comorbid conditions like known case of Type2DM, syst HTN,cancer,active TB, hyperparathyroidism,hypothyroidism,osteoporosis,CKD,CLD,COPD,CAD,CARDIOMYOPATHY,MALABSORPTION,history of allergy from study medication, patients not giving consent for study

Design outcomes

Primary

MeasureTime frame
TO EVALUATE THE EFFECT OF CALCIUM AND VITAMIN D SUPPLEMENTATION ON ADMITTED ACUTE DENGUE FEVER PATIENT ON THEIR PROGRESSION TO DSS AND DHFTimepoint: TO EVALUATE THE EFFECT OF CALCIUM AND VITAMIN D SUPPLEMENTATION ON ADMITTED ACUTE DENGUE FEVER PATIENT ON THEIR PROGRESSION TO DSS AND DHF

Secondary

MeasureTime frame
Progressive worsening of thrombocytopenia,major and minor bleeding episodes,hepatopathy,hypocalcemia,shock,respiratory failure,acute kidney injury,cardiac arrhythmias,encephalopathy,capillary leakageTimepoint: Progressive worsening of thrombocytopenia,major and minor bleeding episodes,hepatopathy,hypocalcemia,shock,respiratory failure,acute kidney injury,cardiac arrhythmias,encephalopathy,capillary leakage

Countries

India

Contacts

Public ContactMilind Raj Nagvanshi

JAWAHARLAL NEHRU MEDICAL COLLEGE AMU ALIGARH

dr.haiderhusaini2k@gmail.com8958786889

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026