the study is comparing two drugs, one called heat stable Carbetocin and the other called Oxytocin, to see which one works better in preventing excessive bleeding after vaginal childbirth by helping the uterus contract properly

Heat stable Carbetocin versus Oxytocin in Active Management of the third stage of Labour to Prevent Postpartum Haemorrhage in women delivering vaginally. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/066741

Enrollment

184

Registered

2024-05-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O721- Other immediate postpartum hemorrhage

Interventions

Intervention1: injection carbetocine: immediately after delivery of baby Heat stable Carbetocin 100mcg IM administered in Active Management of the third stage of Labour to prevent Postpartum haemorrh

Eligibility

Inclusion criteria

Inclusion criteria: Age 18 TO 35 years Pregnant patients with gestational age more than or equal to 37 weeks Singleton pregnancy with cephalic presentation Expected to deliver vaginally with cervical dilatation more than or equal to 5 cm Hemoglobin more than 9gm in recent 3rd trimester report Willing to participate in the study

Exclusion criteria

Exclusion criteria: Previous lower segment caesarean section High risk including antepartum haemorrhage traumatic Postpartum haemorrhage abruption placenta recurrent pregnancy loss multiple pregnancies polyhydramnios perineal or cervical tears during Labour and delivery Medical disorders such as coagulation disorder thrombocytopenia renal disorder hepatic disorder severe cardiac disorder asthma epilepsy Patients with previous uterine surgery Patients requiring blood transfusion before delivery Patient allergy to carbetocin Patients are not willing to sign informed consent

Design outcomes

Primary

Measure	Time frame
THE PROPERTION OF WOMEN HAVING BLOOD LOSS MORE THAN 500 ML WITH IN 2 HOUR OF DELIVERY .Timepoint: THE PROPERTION OF WOMEN HAVING BLOOD LOSS MORE THAN 500 ML WITH IN 2 HOUR OF DELIVERY .	—

Secondary

Measure	Time frame
the proportion of women requiring additional uterotonics in active managment of third stage of labour the proportion of women requiring blood transfusion mean hb difference between the two groups adverse effects of the drug in the two groups after 48 hour . Timepoint: .	—

Countries

India

Contacts

Public ContactDr Suraj Ashokrao Mokade

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, RAIPUR

suraj.mokade1303@gmail.com9321741018

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026