Health Condition 1: B172- Acute hepatitis E
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
ICMR NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES INTRAMURAL GRANT
Eligibility
Inclusion criteria
Inclusion criteria: 1.Clinical suspicion of hepatitis with or without hyperbilirubinemia. 2.Any age 3.Serologically proven hepatitis E infection with detectable Anti HEV IgM antibody irrespective of the presence of other causative factors for hepatitis 4.First visit within 3 weeks of onset of symptoms
Exclusion criteria
Exclusion criteria: 1.Drug induced hepatitis 2.Any other cases of jaundice where Anti HEV IgM antibody is absent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Recovered: Liver function within normal limit in the final follow up, no subjective symptom, 2.Recovered with complications or other organ involvement 3.Recovering: Liver enzymes up to 3 times of the upper normal limit in the final follow up, no/ minimal subjective symptom, 4.Not recovered: Any one or more of persistent symptoms with persistent elevation of liver enzymes, progression to chronic illness in radiological or clinical diagnosis, liver failure with or without coagulopathy 5.Death Timepoint: The patients will be observed in three different time frames. 1.The first visit of the patient will be considered as baseline; this should be within 3 weeks of onset of the symptoms. 2.The second (follow up) visit will be done at 6 weeks of the first visit. 3.The third (follow up) visit will be done at 12 weeks of the first visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| NATimepoint: NA | — |
Countries
India
Contacts
Public ContactDr Sandip Mukhopadhyay
ICMR-NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES
Outcome results
None listed