A clinical trial to study the effect of epidural bupivacaine(local anaesthetic)by interval drug dosing and by patient controlled Analgesia with Epidural Bupivacaine(local anaesthetic)for pain control.

Comparison between Interval Epidural Bupivacaine Top-up and Patient Controlled Analgesia with Epidural Bupivacaine in Critically ill Patients for Analgesia purpose in Intensive Care: A Single blinded Randomised Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/066605

Enrollment

Registered

2024-05-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Epidural topup with Bupivacaine 0.125% BD for 2 days and patient controlled Analgesia with Epidural Bupivacaine 0.125% sos for 2 days: Epidural topup given by primary investigator throu

Eligibility

Inclusion criteria

Inclusion criteria: Age:18-60 years All patients of lower limb surgeries. All patients having major abdominal surgeries and thoracotomy. Patients giving consent for procedure.

Exclusion criteria

Exclusion criteria: Patients with Hypotension, Cardiogenic and Spinal Shock Patients with Septicemia. Mechanically ventilated patients. Patient having coagulopathy/ on anticoagulants /bleeding. Patient with History of head trauma. known allergic to any local anesthetic. Unconcious patient. Refused to give consent for Epidural placement.

Design outcomes

Primary

Measure	Time frame
To compare pain intensityTimepoint: 1st hour and 48 hours	—

Secondary

Measure	Time frame
1.Patient satisfaction 2.Additional analgesic requirementsTimepoint: 48 hours	—

Countries

India

Contacts

Public ContactDR KOMAL SHARMA

AIIMS Rishikesh

ankit.anaes@aiimsrishikesh.edu.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026