Health Condition 1: A90- Dengue fever [classical dengue] Health Condition 2: A91- Dengue hemorrhagic fever
Conditions
Interventions
Intervention1: Plasmalyte-A:
Baseline clinical data and laboratory data will be recorded. Intravenous fluid therapy will be given as per the disease classification.
(1) Dengue with warning signs: P
Sponsors
JAWAHARLAL NEHRU MEDICAL COLLEGE
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosed cases of dengue based on clinical features and laboratory reports (including Dengue IgM,IgG and NS1 levels) requiring intravenous fluid therapy
Exclusion criteria
Exclusion criteria: (1)Comorbid conditions that may affect the outcome of the study like chronic liver disease, congenital heart disease, etc (2) Allergies to Normal saline (0.9%) or Plasmalyte-A (3)Patients with PeLOD-2 score of more than or equal to 14 (4) Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in plasma bicarbonate levelTimepoint: At enrollment and after 6 hours of administration of replacement fluid | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospital stay and in-hospital mortalityTimepoint: till discharge or in-hospital mortality;Glasgow coma scaleTimepoint: 6 hours;Serum electrolytes (Na, K, Ca), urea, creatinine, glucose and haematocrit levelTimepoint: 0 hours and 6 hours;Total volume of fluid received, Fluid rate, urine output and proportion with fluid overloadTimepoint: 6 hours | — |
Countries
India
Contacts
Public ContactHAZIQ AHMAD CHAND
Department of Pediatrics, Jawaharlal Nehru Medical College , AMU, Aligarh
Outcome results
None listed