Modified approach of providing breaths to reduce lung problems under anesthesia in patients undergoing lumbar spine surgeries.

Driving pressure guided ventilation on postoperative pulmonary complications in lumbar spine surgeries: A double blinded randomised control study - DPV

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/066539

Enrollment

Registered

2024-04-30

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Driving pressure ventilation group (DV): Above ventilation will be set along with recruitment which involves gradual increase of PEEP from 5 to 10 and then to 15cm H2O every 5 breaths.

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II patient with well controlled comorbidities;BMI less than 30

Exclusion criteria

Exclusion criteria: Patients with known chronic obstructive pulmonary disease, bronchial asthma, hyperactive airway and interstitial lung diseases ischemic heart disease, severe hepatic or renal dysfunction, musculoskeletal disease.

Design outcomes

Primary

Measure	Time frame
To assess the effect of driving pressure guided ventilation and mechanical power on occurrence of postoperative pulmonary complications in patients undergoing lumbar spine surgeriesTimepoint: Postoperatively patients will be followed up for Postop pulmonary complications at 12 hours, Postoperative day 1, Postoperative day 3 and Postoperative day 7 or at the time of discharge whichever is earliest.	—

Measure

Time frame

To assess the effect of driving pressure guided ventilation and mechanical power on occurrence of postoperative pulmonary complications in patients undergoing lumbar spine surgeriesTimepoint: Postoperatively patients will be followed up for Postop pulmonary complications at 12 hours, Postoperative day 1, Postoperative day 3 and Postoperative day 7 or at the time of discharge whichever is earliest.

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Secondary

Measure	Time frame
To assess the effect of driving pressure on intraoperative hemodynamics between conventional and driving pressure guided ventilation groups.Timepoint: Hemodynamic parameters will be noted every 15 mins intraoperatively till end of surgery .;To assess the effect of respiratory indices,Arterial blood gas(ABG) and Lung ultrasound(LUS), on postoperative pulmonary complications(PPC) occurrence between conventional ventilation group and driving pressure guided ventilation group.Timepoint: Respiratory indices will be noted every 15 mins intraoperatively. Arterial blood gas(ABG) will be done postinduction and pre-extubation. Lung ultrasound(LUS) will be done preinduction,postanaesthesia care unit(PACU) and postoperative day3.	—

Measure

Time frame

To assess the effect of driving pressure on intraoperative hemodynamics between conventional and driving pressure guided ventilation groups.Timepoint: Hemodynamic parameters will be noted every 15 mins intraoperatively till end of surgery .;To assess the effect of respiratory indices,Arterial blood gas(ABG) and Lung ultrasound(LUS), on postoperative pulmonary complications(PPC) occurrence between conventional ventilation group and driving pressure guided ventilation group.Timepoint: Respiratory indices will be noted every 15 mins intraoperatively. Arterial blood gas(ABG) will be done postinduction and pre-extubation. Lung ultrasound(LUS) will be done preinduction,postanaesthesia care unit(PACU) and postoperative day3.

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Countries

India

Contacts

Public ContactStanly Joe Saju

St Johns Medical College and Hospital,Bangalore

drmanjula95@yahoo.com09449059395

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026