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To evaluate the effect of Metoclopramide -a prokinetic and anti emetic drug on the gastric volume after adequate fasting in patients undergoing gynaecological surgeries after spinal anaesthesia

To evaluate the effect of metoclopramide on gastric reserve volume after adequate fasting (8 hours for solids, 2 hours for clear fluids) in patients undergoing gynaecological surgeries under subarachnoid block in a double blind and randomised clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/066529
Enrollment
60
Registered
2024-04-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified Health Condition 2: N819- Female genital prolapse, unspecified Health Condition 3: N72- Inflammatory disease of cervix uteri

Interventions

Intervention1: Injection metoclopramide: Dose-10mg Frequency-once in the preoperative period Route- Intravenous duration of therapy-usg reading taken 30 minutes after intervention Control Intervention

Sponsors

Dr RPGMC Kangra at Tanda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA class I and II BMI 18.5 – 29.9 kg/m2 Mallampati I or II

Exclusion criteria

Exclusion criteria: 1. Patients’ refusal for SAB 2. Patients with cardiovascular or respiratory disorders, diabetes, hypertension 3. Obesity( BMI >29.9kg/m2) 4. Abnormality of upper gastrointestinal tract(GIT) and history of GIT related surgical procedures in the past 5. Use of drugs affecting gastric motility 6. Need for general anaesthesia (GA) due to partial effect of SAB 7. Any contraindication to SAB 8. Cognitive impaired patients 9. History of prolonged QT interval or neuropsychiatric illness

Design outcomes

Primary

MeasureTime frame
The primary outcome will be to observe the quantitative and qualitative change in gastric antrum as assessed by the US of gastric antrum to estimate gastric volume after standard dose of metoclopramide ie calculation of CSA in right lateral and supine positionTimepoint: baseline and 30 minutes after intervention—

Secondary

MeasureTime frame
1.Incidence of complete gastric emptying 2.Incidence of episodes of intraoperative and postoperative nausea and vomiting after gynaecological surgeries correlated with Metoclopramide administration and gastric volume 3.Adverse outcomes-Number of adverse events like abdominal cramping, extrapyramidal symptoms between the two group Timepoint: 24 hours after administration of drug—

Countries

India

Contacts

Public ContactDr Shelly Rana

Dr Rajendra Prasad Government Medical College Kangra at Tanda

shelgnbj@gmail.com9418113786

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026