Comparison of Desflurane ( a inhalational anesthetic agent) and Propofol ( a intravenous anaesthetic agent) in adult patients undergoing lumbar spine surgeries under general anesthesia. The emergence and recovery characteristics are compared among patients.

Comparision of Desflurane and Propofol for emergence and recovery characteristics in adult patients undergoing lumbar spine surgeries under general anaesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/066479

Enrollment

Registered

2024-04-29

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Desflurane , Propofol: As general anaesthetic agents in adult patients undergoing lumbar spine surgeries. Control Intervention1: DESFLURANE , PROPOFOL: Desflurane a inhalational anaesth

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing lumbar spine surgeries under General Anaesthesia. ASA physical status I and II

Exclusion criteria

Exclusion criteria: Significant cardiovascular , respiratory, hepatic, renal, neurological, psychiatric or metabolic. Documented allergic reaction to the anaesthetic agent being used.

Design outcomes

Primary

Measure	Time frame
Comparing â??Modified Aldrete Score ? between both the groups after extubation.Timepoint: AT 10Min, 20Min and 30Min	—

Secondary

Measure	Time frame
Compare time to extubation, spontaneous eye opening & response to verbal commands after switching off the anaesthetic agent. Compare intraoperative hemodynamic stability by monitoring SBP, DBP, MAP, HR. Compare requirement of blood products, total requirement of intravenous fluids, need for vasopressor & inotropes intra operatively Visual Analogue Scale (VAS) scores at the time of discharge from post anaesthetic care unit (PACU) & Incidence of post operative nausea vomiting (PONV) Timepoint: From the time of switching off the anesthetic agent the time taken will be recorded for extubation, eye opening & response to verbal command.	—

Measure

Time frame

Compare time to extubation, spontaneous eye opening & response to verbal commands after switching off the anaesthetic agent. Compare intraoperative hemodynamic stability by monitoring SBP, DBP, MAP, HR. Compare requirement of blood products, total requirement of intravenous fluids, need for vasopressor & inotropes intra operatively Visual Analogue Scale (VAS) scores at the time of discharge from post anaesthetic care unit (PACU) & Incidence of post operative nausea vomiting (PONV) Timepoint: From the time of switching off the anesthetic agent the time taken will be recorded for extubation, eye opening & response to verbal command.

—

Countries

India

Contacts

Public ContactAvanish Bhardwaj

Command Hospital Air Force Bangalore

avanishbhardwaj78@gmail.com9914734466

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026