Health Condition 1: C068- Malignant neoplasm of overlappingsites of other and unspecified parts of mouth
Conditions
Interventions
Intervention1: Intra-arterial chemotherapy: Cisplatin, a chemotherapeutic agent, will be given through the intra-arterial route in the Cath lab. It will be given in 3 weekly cycles. Two to three cycle
Sponsors
Department Of Science Technology and renewable energy chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with confirmed diagnosis of advanced-stage (IVa/IVb) OSCC and surgically inoperable 2. Patients aged 18–80 years old will be included in the study. 3. Patients expected to comply with the protocol 4.Patient willing to enroll in the study
Exclusion criteria
Exclusion criteria: 1. Patients with a history of previous treatment (surgery, chemotherapy, or radiotherapy) of oral cancer. 2. Pregnant patient, lactating mother or planning to be pregnant 3. Drug abusers or any other substance abuse 4. Patient with any psychiatric disorder or undergoing any psychiatric treatment 5. Patients with terminal illness whose prognosis of survival is less than a year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical and radiological response to chemotherapy.Timepoint: Pre-intervention, 2 weeks after the second cycle of chemotherapy, 2 weeks after 3rd Cycle (if given) | — |
Secondary
| Measure | Time frame |
|---|---|
| Toxicity assessment Histopathological response.Timepoint: 2 weeks after completion of chemotherapy | — |
Countries
India
Contacts
Public ContactDr Anand Gupta
Govt medical college hospital Chandigarh
Outcome results
None listed