Health Condition 1: C690- Malignant neoplasm of conjunctiva
Conditions
Interventions
Intervention1: Topical Mitomycin C 0.04%: Topical Mitomycin C (alkylating agent) eye drops in 0.04% given topically 4 times a day for 4 days a week for 4 weeks followed by 2 weeks drug holiday in ocul
Sponsors
Dr Shroff Charity Eye Hospital
Eligibility
Inclusion criteria
Inclusion criteria: All patients above 18 years of age diagnosed with ocular surface squamous neoplasia without scleral or orbital invasion with no history of prior treatment for presenting lesion
Exclusion criteria
Exclusion criteria: 1)patients with previous history of receiving treatment for presenting lesion 2)patients with advanced cases of ocular surface squamous neoplasia with scleral or orbital invasion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)% reduction in tumor dimensions(in terms of maximum vertical , horizontal dimensions and thickness) at 2 months and 3 months of starting therapy Timepoint: 1)% reduction in tumor dimensions(in terms of maximum vertical , horizontal dimensions and thickness) at 2 months and 3 months of starting therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)time taken to complete clinical resolution of tumor 2)side effects/toxicity profile of each drug at the end of the studyTimepoint: 1) time taken for complete clinical resolution is variable 2)side effect profile at end of study i.e. 1 year 6 months from start | — |
Countries
India
Contacts
Public ContactKhyati Roop
Dr Shroff Charity Eye Hospital
Outcome results
None listed