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A Prospective Study to Evaluate the Role of Acute Phase Reactants in the Management of Odontogenic Space Infections

A Prospective Study To Evaluate The Role Of Acute Phase Reactants In The Management Of Odontogenic Space Infections - APSERAPRMOSI

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/04/066299
Enrollment
32
Registered
2024-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K047- Periapical abscess without sinus

Interventions

Control Intervention1: preoperative and postoperative values of serum procalcitonin , ESR , CRP ,TLC: preoperative and postoperative values of serum procalcitonin , ESR , CRP ,TLC after incision and d

Sponsors

Punjab Government Dental College and Hospital,Amritsar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Male or female patients, aged 19 years or older with fascial space infection of odontogenic origin. 2. Any carious/ periodontally compromised teeth which can be considered as foci of infection. 3. Patients falling in ASA class 1, 2 and 3. 4. Patients willing for procedure and subsequent follow ups.

Exclusion criteria

Exclusion criteria: 1. Patients falling in ASA class 4 and 5. 2. Patents who are on oral / I.V antibiotic therapy prior to blood investigations. 3. Patients on long term steroids. 4. Patients who are pregnant. 5. Patients with facial space infection of non odontogenic origin. 6. Patients previously radiated maxillofacial region. 7. Patents who are not willing to give consent.

Design outcomes

Primary

MeasureTime frame
Patient’s CBC, ESR, CRP and serum procalcitonin levels will be evaluated on 1st day followed by incision and drainage and /or extraction of offending tooth. Patient’s post operative levels of CBC, ESR, CRP and serum procalcitonin will be evaluated on the 5th day after interventionTimepoint: 1st day , 5th day

Secondary

MeasureTime frame
other postoperative parameters include 1.) Maximum mouth opening.2.) Swelling 3.) PainTimepoint: patient will be followed up on first, third, fifth, seventh and tenth post-operative day

Countries

India

Contacts

Public ContactDr Nitin Verma

Punjab Government Dental College and Hospital, Amritsar

nitinvermagdc@gmail.com9814164068

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026