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Intrauterine insemination done 36 and 42 hours after human chorionic gonadotropin injection in unexplained infertility

Comparison of intrauterine insemination done 36 and 42 hours after human chorionic gonadotropin injection in unexplained infertility: a randomized clinical trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/066281
Enrollment
100
Registered
2024-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: In-utero insemination: Once after 36 hours and 42 hours after HCG Control Intervention1: Biochemical and clinical pregnancy rate: Once after 2 weeks

Sponsors

University College of Medical Sciences and Guru Teg Bahadur Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosed cases of unexplained infertility a) Documented ovulation b) At least one patent tube c) Normal uterine cavity d) Normal semen analysis 2. Age: 20-38 years 3. Normal ovarian reserve

Exclusion criteria

Exclusion criteria: 1. Any medical condition contraindicating pregnancy. 2. Endocrine disorders such as uncontrolled hypothyroidism or diabetes mellitus. 3. Active infections such as pelvic inflammatory disease, vaginal or cervical infection. 4. The presence of four or more dominant follicles in the ultrasound imaging before HCG injection. 5. No dominant follicles in the stimulated cycle.

Design outcomes

Primary

MeasureTime frame
1. Comparison of Biochemical pregnancy rates in percentage in both groups (based on the period between HCG injection and IUI) of unexplained infertility. 2. Comparison of Clinical pregnancy rates in percentage in both groups (based on the period between HCG injection and IUI) of unexplained infertility.Timepoint: after 2 weeks

Secondary

MeasureTime frame
1. Comparison of Documented Ovulation in percentage (signs of ovulation on USG) on the day of IUI in both the groups. 2. Comparison of Biochemical and clinical pregnancy rates in percentage in IUI done with and without documented ovulation.Timepoint: Same day and after 2 weeks

Countries

India

Contacts

Public ContactDr Rashmi

UCMS and GTB Hospital

rashmi.malik2011@gmail.com9810645212

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026